The Golden Age of Collagen Boosters: What Really Makes a Difference?

For those who want to add volume, but want to do it with their own collagen..!

They visit the clinic after searching for collagen boosters.

Next, there is a question I hear.

I want to use a collagen booster, but I don't know what's what.

Various types of collagen boosters

Juve Look Volume, Sculptra, Radius, Elancé.

You must have all heard the name, The ingredients, the timing of volume development, the duration, and the side effects are all different.

Today, I will compare these four based on the criteria I established while performing the procedures myself.

The graph above shows a relative evaluation of four products based on six criteria.

I will explain below, one by one, why I gave this score.

How are collagen boosters different from fillers?

Hyaluronic acid fillers immediately fill the space by injecting an externally produced gel.

You can trim the shape while monitoring it during the procedure, and if you are not satisfied, you can dissolve it with enzymes.

Collagen boosters have similar purposes but different directions.

Instead of filling it in, it stimulates the skin to produce collagen on its own.

So it takes time for the results to come out, but instead, they last a long time.

and Once created, my collagen cannot be dissolved.

If you keep just these two things in mind, the comparison below will be much easier.

1. The ingredients are different starting from the start - PDLLA, PLLA, CaHA, PCL

All four are called "Collagen Boosters," but the ingredients inside are all different.

1. Jube Look Volume - PDLLA (Polydielactic Acid) 170mg + Hyaluronic Acid 30mg. It is an amorphous, non-crystalline, hollow, porous network-structured particle.

2. Sculptra - PLLA (Polylactic Acid). A material used in surgical sutures, prepared by hydrating freeze-dried powder with water for injection.

3. Radius - Approx. 30% CaHA (Calcium Hydroxyapatite) microspheres + Approx. 70% CMC gel. It consists of components similar to the minerals that make up bones and teeth.

4. Elancé - PCL (Polycaprolactone) beads + CMC gel. This is also a material that has been used as a suture for a long time.

All four are components that break down and disappear from the body.

The difference is Particle shape, decomposition rate, and whether gel is includedno see.

Radiesse and Ellanse, which contain gel, show volume immediately after injection.

With Juvelux Volume and Sculptra, which are powders that are hydrated and added, there comes a time during the first few days when the color fades, making you think, "Huh? Did it disappear?"

This difference leads to number 2 below.

2. When does volume develop? - Early volume and late volume

This is the first criterion I look at when classifying your products.

1. Immediate type (Radius, Ellanse) - CMC gel creates volume immediately after injection, and as the gel is absorbed over several weeks, the particles produce collagen to take over the space. Volume is maintained both immediately after the procedure and two months later.

2. Delayed type (Jubeyuk Volume, Sculptra) - The volume immediately after the procedure is achieved using saline solution and sterile water for injection. It is absorbed within 1 to 2 days, and collagen begins to increase starting from 2 weeks. Juvereign volume is most pronounced around 8 weeks, and biopsy results for Sculptra show a 66% increase in collagen at the 3-month mark.

so If there is a wedding or a blind date in a week, I am the immediate type.This is correct,

If you want to improve gradually without rushing or noticing, choose the delayed typeThis is correct.

Many people think that "the volume disappeared" two days after receiving the delayed type, but this is normal.

The real volume gradually fills up over time.

The effects of the product can be divided into stages as follows:

This is what the skin cross-section diagram on the detail page looks like. From left to right, the images show the day of the procedure → several weeks later → a long period, and the layers from top to bottom are the epidermis, dermis, and subcutaneous layer.

3. How long does it last? - Duration

• Jube Look Volume - PDLLA breakdown standard in the body: 12–16 months

• Sculptra - The maximum biodegradation period for PLLA is 25 months. In a biopsy at 30 months, collagen fills the spaces where the particles were located.

• Radius - Over 2 years. Dermal thickness measured by ultrasound increased by approximately 12% after 4 months and 27% after 7 months (manufacturer's data).

• Elancé - 18 months or older. Choose type S or M depending on the area and desired duration.

I will check one thing here before moving on.

The duration is the period during which the particles break down, not the period during which the volume remains the same as it was initially.

Since the collagen produced also gradually decreases with aging, it is more accurate to understand it as "lasting longer than other products" rather than focusing on the numbers.

The longest-lasting ones are Sculptra and Radius, followed by Elancé, and then Juvelook Volume.

However, since Juvelux Volume breaks down quickly, it remains in the body for a short period.

4. Safety and Side Effects

Swelling lasts 2–3 days, bruising lasts 1–2 weeks, and a pain level of 3 out of 5 is similar across the four products.

The difference lies in the nodules, massage, and whether the institution is approved.

First, the most important thing.

None of the four products can be dissolved by enzymes like hyaluronic acid fillers.

So, instead of putting in a lot at once, I divide it into smaller amounts and put in several times.

1. Sculptra - Nodules may form if dilution is insufficient or the injection is shallow. Massage is required for 5 minutes, 5 times a day, for 5 days after the procedure.

2. Jube Look Volume - Since PDLLA is amorphous and does not form crystals, it clumps less, but it may be visible if applied to shallow layers. The massage is 5-5-5, the same as Sculptra.

3. Radius - Smooth spherical microspheres of 25~45㎛ naturally settle at the injection site.

4. Elancé - Since bead-shaped PCL is mixed into the gel, massage is not necessary. However, particles may be palpable if applied to thin areas.

You also need to check whether the certification body has approved it.

Just because something has been used for a long time doesn't necessarily mean it's good, but The fact that it has been used for a long time means that data has accumulated to that extent.no see.

• Sculptra - Approved by the US FDA in 2004 and 2009. Approved by the Korean Ministry of Food and Drug Safety in 2010.

• Radius - Approved by the U.S. FDA in 2006. Authorized by the Korean Ministry of Food and Drug Safety. Used in over 80 countries.

• Elancé - European CE, Korean Ministry of Food and Drug Safety approval. There is no US FDA approval yet.

• Jube Look Volume - Approved by the Ministry of Food and Drug Safety. The manufacturing technology for the network structure is registered as a domestic patent (No. 10-1725279).

So the "Permission, Approval Status" parameter of the graph is Sculptraand RadiusIt is the highest.

If skilled medical personnel sufficiently dilute and distribute evenly in the correct layers, the probability of side effects for all four is low.

at last A procedure where the practitioner's skill is more important than the productno see.

5. Which areas can be treated?

All four products are available for the cheekbones, front cheeks, side cheeks, nasolabial folds, and marionette lines.

The places where you don't insert it are the under-eyes, eyelids, and lips.

The skin in this area is thin, so particles may be palpable or it may appear bumpy.

If this area needs volume, it is appropriate to use a soft hyaluronic acid filler.

Collagen boosters and fillers are mutually interchangeable, but they are also complementary.

6. How many times should I receive it, and what will the cost be?

1. Jube Look Volume - At 1-month intervals, a total of 3 times

2. Sculptra - At intervals of 4 to 6 weeks, 3 to 4 times

3. Radius - Recommended 3 times at 1-month intervals.

4. Elancé - Usually once. Re-treatment is performed when the effect diminishes.

There is sometimes an easy misconception when looking at costs.

You should compare based on the total amount calculated by multiplying the number of sessions by the capacity, rather than the price per session.

There are products that may seem cheap per session but require all three sessions to produce results, and there are products that are expensive per session but can be completed in just one session.

For reference, the market price range is as follows.

It varies from hospital to hospital and changes depending on the time of year, so please consider this as a general range.

• Jube Look Volume - 300,000–600,000 won based on 8cc. 1,200,000–1,800,000 won based on 3 sessions

• Sculptra - 700,000 to 1,000,000 won per vial (10cc). 2,100,000 to 3,000,000 won based on 3 uses of 10cc

• Radius - 1.4 to 2 million won based on 2 syringes (3cc)

• Elancé - 500,000 to 1,000,000 won per 1cc. 2,000,000 to 4,000,000 won based on 4cc

Looking at it this way, the cheapest per session is Juvelook Volume, and the highest total amount is Elancé.

The "low cost burden" item in the graph was determined based on this total amount.

7. Compare at a glance

8. So, which one would be good for me?

• I have an urgent schedule. - Radiesse, Ellanse. There is a volume effect immediately after the procedure, followed by collagen regeneration.

• You can come to the hospital three times, gradually and unnoticed. - Juve Look Volume, Sculptra

• I want to get it once and it lasts a long time. - Elancé

• My whole face is sunken and I want the longest-lasting one. - Sculptra

• Skin thickness and elasticity rather than volume, back of hands and neck - Radius Dilution Injection

• I find fillers burdensome and want to reduce the cost. - Jube Look Volume

You can find out which collagen booster suits you best just by following the algorithm above!!

In the EPISODE, all four products Verify the authenticity and dosage right before your eyes before the procedure.Then, record the solution used for hydration and the injection volume for each site in the procedure report.

9. Frequently Asked Questions

Q. Can I get this at the same time as hyaluronic acid fillers?

Yes, it is possible. They are complementary, not substitutes. It is a good approach to use fillers for thin areas like under the eyes and lips, and collagen boosters for wider areas like the cheeks and cheekbones.

Q. Can I melt it if I don't like the result?

All four products cannot be dissolved. Therefore, instead of adding a large amount at once, inject small amounts multiple times.

Q. Is a massage mandatory?

Please apply Juvelook Volume and Sculptra gently for 5 minutes, 5 times a day, for 5 days. Rubbing too hard may cause the particles to clump to one side.

Q. Is it normal that the volume decreased the day after the procedure?

Juvereign Volume and Sculptra are normal. It is a process where the water used for hydration is released, and collagen begins to increase starting from the second week.

Q. When can I receive lifting procedures after this treatment?

Please avoid strong pressure, radio frequency, and ultrasound lifting on the treated area for two weeks after the procedure. The particles need time to settle.

Q. Are there cases where it should not be received?

Please be sure to inform us during your appointment if you have an infection at the procedure site, connective tissue disease, an autoimmune disease, or are pregnant or breastfeeding. Radiesse is also suitable for individuals with a predisposition to keloids.

10. In conclusion..

To summarize, it is as follows.

'filled' It's not that, but 'I'll make itIt is a procedure that takes time, but it lasts a long time.

gel Radius, ElancéIt immediately shows a certain degree of volume effect.

Hydrating powdered particles and injecting them Juve Look Volume, SculptraIt takes about 2 months or more to create the volume.

Also, since you cannot melt all four, you must put them in small amounts, divided, and in precise layers.

The golden age of collagen boosters. We looked into which collagen booster is truly the most suitable for me.

This has been Seo Min-ho. Thank you for reading.