EPISODE CLINIC
Ko

Rejuran HB

Rejuran HB

Rejuran HB
#Moisturizing #SkinTexture #FineWrinkles #PN+HA

Recovery and hydration at the same time

Rejuran HB

Rejuran HB


Rejuran HB is a medical device that combines hyaluronic acid (HA) with PN (Polynucleotide) , a DNA fragment obtained from salmon. PN helps the skin recover, while HA retains moisture to prevent the skin from drying out.

PN is known as a highly biocompatible material because its base composition is 97% similar to that of human DNA.1) Inside the dermis Scaffold roleWhile doing so, the hyaluronic acid included together maintains the moisture in between.

HB is a product that adds moisturizing benefits to Rejuran Original, which aids in recovery. With at least three treatments at one-month intervals, skin texture and fine lines gradually improve with each subsequent session. It is particularly well-suited for those experiencing overall skin improvement and frequent dryness.

1) The composition of the deoxyribonucleic acid of salmon sperm, Erwin Chargaff, 1951.

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Why Rejuran HB

Four Reasons to Choose Rejuran HB

Even the same ' Skin Booster'
The ingredients and effects vary from product to product.

PN polynucleotide
01

It comes from the DNA closest to humans.

The main ingredient of Rejuran, PN, is a DNA fragment extracted from salmon. Among various fish species, it is known to be the material with the relatively low risk of foreign body sensation or rejection reaction because its base composition is closest to that of humans .

The similarity in DNA base composition between humans and salmon is reported to be approximately 97%.

DOT DNA Optimizing Technology
02

It is an ingredient made to match even the molecular weight.

Even within the same PN, properties vary depending on the length of the DNA fragment. Rejuran is the manufacturer's patented technology DOT®(DNA Optimizing Technology)We manufacture products by adjusting the molecular weight range to suit their specific uses.

* DOT®is a registered patented technology of the manufacturer (Pharmaresearch).

Tissue repair effect
03

Tissue repair effect

It was confirmed that facial wrinkles temporarily improved as tissues recovered after Rejuran was injected. An increase in tissue density was also observed.

* Joon Min Jung, Chong Hyun Won, 2020. Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double blind, split face trial. Journal of Dermatological Treatment
* Data on file, Bundang Seoul National University Oral Wrinkle Clinical Trial, 2019

Hyaluronic acid
04

Hyaluronic acid was added to this.

Rejuran HB is a product that combines PN with hyaluronic acid (HA) . While the skin recovers with PN, hyaluronic acid retains moisture within the dermis, preventing the skin from drying out during the recovery process .

* HA: Hyaluronic Acid. It is a component naturally found in the skin and connective tissue, and is known to be able to hold hundreds of times its own weight in water.

Line Up

Rejuran product lineup

Choose from four options depending on the purpose and area of ​​the treatment .
Rejuran HB is a product that also addresses moisturization among these.

Rejuran

Rejuran

PN 40mg / 2mL

This is the basic form of Rejuran. It contains only PN ingredients , so you can receive it without any burden when you want to improve your overall facial skin.

Expected effectsImprovement of fine lines, skin texture You guys33G 4mm
Rejuran Eye

Rejuran i

PN 20mg / 1mL

This product was released specifically for the eye area and under the eyes . It uses finer needles, making it ideal for use in the thin skin around and under the eyes.

Expected effectsImprovement of fine lines around the eyes You guys34G 4mm
Rejuran S

Rejuran s

PN 20mg / 1mL

This product is designed to stay on the localized area for a longer period by increasing viscosity . It uses long needles to fill in from the deep layers.

Expected effectsImprovement of indentations and curves You guys30G 8mm
Rejuran HB

Rejuran HB

PN 10mg + HA 10mg
/ 1mL

This product enhances moisturizing power by adding hyaluronic acid to PN. We also have HB plus , which contains lidocaine, available, so please let us know during your consultation if you are sensitive to pain.

Expected effectsMoisturizing effect, improvement of fine lines You guys33G 4mm

* PN: Polynucleotide, the main ingredient of Rejuran. HA: Hyaluronic Acid.
Rejuran HB Plus has the same ingredient composition as Rejuran HB, but with the addition of Lidocaine 2.8mg/1mL. Please be sure to inform us during your consultation if you have experienced adverse reaction to local anesthetics.
The product and dosage are determined after a medical consultation, and the above information is a summary of the approved specifications provided by the manufacturer.

How It Works

Mechanism of Action of Rejuran HB

1
Principle of Operation Stage 1

The injected PN and HA first
It supports the skin from within.

High molecular weight PN acts as a temporary support within the dermis, while the accompanying hyaluronic acid attracts moisture, helping the extracellular matrix recover during this time.

2
Operating principle, 2 stages

The component released from the decomposition of PN
It helps with tissue recovery.

The components produced from the breakdown of PN activate cell regeneration signals to regulate inflammation and help increase fibroblasts and collagen, thereby accelerating tissue recovery.

3
3-step operating principle

The decomposed DNA components are
It is reused as a material to restore cells.

Nucleotides and nucleosides degraded from PN are recycled into the salvage pathway and used for DNA synthesis and the repair of damaged cells.

Treatment Areas

Rejuran HB treatment site

It is mainly used on areas where the skin is thin or has a rough texture.

Rejuran HB treatment site
Butterfly Zone 2cc
Both both cheeks 4cc
The entire face (including the forehead) 6cc

1cc fits one business card size (9cm x 5cm) area.

Recommended For

I recommend this to people like this.

inner tightness and dryness
The person who feels it

My makeup looks cakey and the texture is
Those who feel they have become rough

Increased fine wrinkles
Those who feel the same

Skin texture and skin condition
Those who want to modify the structure

Doctor's Column

Treatment Stories written personally by the Director

This is a text written directly by the Director who actually performs this treatment , detailing the principles and standards.

Not only the results, but even the difference in experience

The Episode Difference

Why It's Different

Every process has its own reason for the EPISODE.

01

REJUVENATION CLUB
This is a VIP hospital.

REJUVENATION CLUB VIP Hospital

Having worked extensively with Rejuran and being recognized for my contribution to its development , Operated by Rejuran We are serving as a VIP hospital for the Rejuvenation Club.

CERTIFIED

02

Authenticity verification
I confirm it right before my eyes.

Check product and capacity

You can verify the authenticity of Rejuran HB using the QR code on the box and the NFC tag on the blister. We will check it together before opening, and we will show you the exact capacity you need.

RELIABILITY

03

By case number
I prove it.

Rejuran HB treatment experience

EPISODE CLINIC has been using Rejuran HB. I have used it a lot. You can check the usage directly by visiting the in-hospital lounge.

EVIDENCE

04

The more sessions a treatment accumulates, the more
Records are important.

Online treatment Report

Since it is a treatment that requires multiple sessions, the products used and quantities for each session, I am documenting my skin changes in an online report. The plan for the next session is also determined based on this record.

RECORDS

Care Process

Rejuran HB proceeds through this process.

01

Skin diagnosis

02

Anesthesia process

03

treatment

04

Modeling pack

05

homecoming

06

Provision of treatment report

Some processes will be changed for the promotional treatment.

Notice

Please observe these points after the treatment .

  • 1

    The injection site will bulge immediately after the treatment . It usually subsides within a day, so please do not rub or press it to flatten it.

  • 2

    Please avoid wearing makeup on the day of the treatment . Please wash your face gently with lukewarm water starting 4 hours after the treatment .

  • 3

    Please avoid alcohol, strenuous exercise, and saunas for 24 hours after the treatment . Swelling and bruising may worsen.

  • 4

    Swelling usually subsides within 1-2 days , and bruising within 1-2 weeks . Bruising around the eyes may last longer than on other areas.

  • 5

    Please pay special attention to sun protection and moisturizing for one week after the treatment . It is best to avoid harsh exfoliation, peeling, and hot compresses.

  • 6

    This is not a one-time treatment . We recommend at least three sessions at one-month intervals, and subsequent intervals will be adjusted according to your condition. If the treatment is performed using HB Plus containing lidocaine, please be sure to inform us beforehand if you have experienced adverse reaction to local anesthetics.

  • 7

    If severe pain, heat, or redness at the injection site persists or worsens, please contact the hospital immediately.