Rejuran
Rejuran
Improves the skin base of thin and rough skin.
Rejuran
Rejuran
Rejuran is a medical device whose main component is PN (Polynucleotide) , a DNA fragment derived from salmon. It is not a treatment that fills in sunken areas to reshape the face. Instead, it is a treatment that maintains the facial shape while comprehensively improving the skin's internal environment to allow it to recover.
PN is in the form of a colorless, transparent gel that maintains a constant viscosity, in the dermis Scaffold role...is known as a highly biocompatible material because its base composition is 97% similar to human DNA.1)
If you receive at least 3 sessions at 1-month intervals, your skin texture and fine lines will gradually improve as the sessions accumulate. Since this treatment elevates your overall skin condition, it is used to address your skin's general state , including recovery.
1) The composition of the deoxyribonucleic acid of salmon sperm, Erwin Chargaff, 1951.
Why Rejuran
Three Reasons to Choose Rejuran
Among ' Skin Booster ', Rejuran
This is a treatment using PN components.
It comes from the DNA closest to humans.
The main ingredient of Rejuran, PN, is a DNA fragment extracted from salmon. Among various fish species, it is known to be the material with the relatively low risk of foreign body sensation or rejection reaction because its base composition is closest to that of humans .
The similarity in DNA base composition between humans and salmon is reported to be approximately 97%.
It is an ingredient made to match even the molecular weight.
Even within the same PN, properties vary depending on the length of the DNA fragment. Rejuran is the manufacturer's patented technology DOT®(DNA Optimizing Technology)Each product is manufactured to match the molecular weight range suitable for its intended purpose.
* DOT®is a registered patented technology of the manufacturer (Pharmaresearch).
Tissue repair effect
When Rejuran is injected, temporary improvement in facial wrinkles can be observed due to the tissue repair effect. An increase in tissue density is also observed.
* Joon Min Jung, Chong Hyun Won, 2020. Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double blind, split face trial. Journal of Dermatological Treatment
* Data on file, Bundang Seoul National University Oral Wrinkle Clinical Trial, 2019
Line Up
Rejuran product lineup
Choose from four options depending on the purpose and area of the treatment .
Rejuran
PN 40mg / 2mLThis is the basic form of Rejuran. It consists solely of PN ingredients and is suitable for those who want to improve their overall skin without any burden.
Rejuran i
PN 20mg / 1mLThis product is designed specifically for the eye area and under the eyes . It uses finer needles to perform the treatment on the thin skin around and under the eyes.
Rejuran s
PN 20mg / 1mLThis product is designed to stay on the localized area for a longer period by increasing viscosity . It uses long needles to fill in from the deep layers.
Rejuran HB plus
PN 10mg + HA 10mg+ Lidocaine 2.8mg / 1mL
This product enhances moisturizing power by adding hyaluronic acid to PN. It contains lidocaine, making the pain during the treatment relatively less burdensome.
* PN: Polynucleotide, the main ingredient of Rejuran.
Rejuran HB plus contains 2.8 mg/1 mL of lidocaine. Please be sure to inform us during your consultation if you have experienced adverse reaction to local anesthetics.
Product selection and dosage are determined after a medical consultation, and the above information is a summary of the approved specifications provided by the manufacturer.
How It Works
The mechanism of action of Rejuran
The injected PN itself
It creates a supporting environment within the skin.
The high molecular weight PN attracts moisture and acts as a temporary support within the dermis, creating a favorable environment for the extracellular matrix to recover.
The degradation products of PN activate the regeneration signal
Promotes tissue recovery
The components released from the breakdown of PN activate cell regeneration signaling pathways to regulate inflammation and promote tissue recovery by increasing the production of fibroblasts and collagen.
Reusing decomposed DNA components
It is used as a cell repair material.
Nucleotides and nucleosides degraded from PN are reused in the salvage pathway for DNA synthesis and the repair of damaged cells.
Treatment Areas
Rejuran treatment site
It is mainly used on areas where the skin is thin or has a rough texture.
1cc fits one business card size (9cm x 5cm) area.
Recommended For
I recommend this to people like this.
No need to worry about volume
For those who want to improve their skin condition
My makeup looks cakey and the texture is
Those who feel they have become rough
Overall skin condition
Those who want to improve
My skin is sensitive
For those who are cautious about choosing a treatment
Doctor's Column
Treatment Stories written personally by the Director
This is a text written directly by the Director who actually performs this treatment , detailing the principles and standards.
Skin Booster: Ingredients and Differences by Type
Skin Booster Comparison Based on Hyaluronic Acid, PN, PDRN, Exosome , and PDLLA
Chief Director Seo Min-ho | EPISODE CLINIC
What are the types and differences of Rejuran?
Comparison of Rejuran, Rejuran i, Rejuran HB, and Rejuran S
Chief Director Seo Min-ho | EPISODE CLINIC
Rejuran, skin glow injection, and Skin Botox all at once, painlessly?
Skin Texture Therapy (Why it mixes right in front of your eyes, why it hurts less)
Chief Director Seo Min-ho | EPISODE CLINIC
The Episode Difference
Why It's Different
Every process has its own reason for the EPISODE.
01
REJUVENATION CLUB
This is a VIP hospital.
Recognized for extensive clinical experience with Rejuran and contributions to its development. Operated by Rejuran We are serving as a VIP hospital for the Rejuvenation Club.
CERTIFIED02
Authenticity verification
I confirm it right before my eyes.
You can verify the authenticity of Rejuran using the QR code on the box and the NFC tag on the blister. We will check it together before opening and show you the exact capacity you need.
RELIABILITY03
By case number
I prove it.
EPISODE CLINIC's Rejuran treatment is I will show you the amount I have used so far. You can check it for yourself if you visit the in-hospital lounge.
EVIDENCE04
The more sessions a treatment accumulates, the more
Records are important.
Since it is a treatment that requires multiple sessions, the products used and quantities for each session, I am documenting my skin changes in an online report. The plan for the next session is also determined based on this record.
RECORDSCare Process
Rejuran proceeds through this process.
01
Skin diagnosis
02
Anesthesia process
03
treatment
04
Modeling pack
05
homecoming
06
Provision of treatment report
Some processes will be changed for the promotional treatment.
Notice
Please observe these points after the treatment .
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1
The injection site will bulge immediately after the treatment . It usually subsides within a day, so please do not rub or press it to flatten it.
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2
Please avoid wearing makeup on the day of the treatment . Please wash your face gently with lukewarm water starting 4 hours after the treatment .
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3
Please avoid alcohol, strenuous exercise, and saunas for 24 hours after the treatment . Swelling and bruising may worsen.
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4
Swelling usually subsides within 1-2 days , and bruising within 1-2 weeks . Bruising around the eyes may last longer than on other areas.
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5
Please pay special attention to sun protection and moisturizing for one week after the treatment . It is best to avoid harsh exfoliation, peeling, and hot compresses.
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6
This is not a one-time treatment. We recommend at least three sessions at one-month intervals, and thereafter, the intervals will be adjusted according to your condition.
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7
If severe pain, heat, or redness at the injection site persists or worsens, please contact the hospital immediately.